PCOS and Gluten: Navigating The Myths and Facts

pcos and gluten

Written by Oleska Prokopovych, RD, MAN(c)

Reviewed by
Olivia Farrow, RD, MHSc
Krista Kolodziejzyk, RD, MPH, MBA
Maria Dellanina, RDN

There are various claims online about PCOS and gluten; that eating gluten-containing foods is harmful for people with polycystic ovary syndrome (PCOS). In this article, we break down the myths and research evidence related to PCOS and gluten.

Learn more about how to support your clients with PCOS and discover evidence-based nutrition therapy interventions with our comprehensive PCOS Nutrition Course, exclusively available through the Dietitian Success Center membership.


What Is PCOS?

Polycystic ovary syndrome (PCOS) is a disorder found in people with ovaries that affects the endocrine gland, which creates and secretes hormones into the bloodstream (1). PCOS is a common disorder with an estimated global prevalence of 3-10% (2). Individuals with PCOS have an increased risk of developing heart disease (2) and type 2 diabetes (2,3,4).

The condition is commonly associated with the following traits (1):

      • A cluster of cysts (fluid-filled pockets) on the ovaries 

      • Irregular periods and subfertility (failure to conceive after 1 year of unprotected intercourse)

      • High levels of testosterone 

      • High levels of androgens, which can cause acne, hair loss, and/or excessive hair growth on the face and body

      • Mental health challenges (e.g. anxiety, depression, disordered eating)

    The Dietitian Success Center membership includes access to many resources for dietitians. Our PCOS course includes a thorough summary of current evidence on nutrition therapy for PCOS, a 3-part video course, and client-facing handouts. To learn more about PCOS nutrition therapy, check out the DSC PCOS nutrition course.


    What is Gluten?

    Gluten is a protein found in wheat, rye, and barley. Gluten-containing foods should be avoided to varying degrees by those who have celiac disease, non-celiac gluten sensitivity, or a wheat allergy. Those with celiac disease must avoid gluten completely (5). 

    You may find that clients have read articles online reporting that eating a gluten-free diet is beneficial for PCOS management. These anecdotal sources claim that people with PCOS are more likely to have gluten sensitivity. Some articles also claim that a gluten-free diet will help with weight loss, inflammation, hormone balance, period regularity, fatigue, and more. However, current research on PCOS and gluten is highly limited, and not robust enough to make any definitive claims. 

    Using the most relevant research studies available, let’s bust some of the myths about PCOS and gluten. 


    Myths About PCOS and Gluten

    MYTH: “There is a link between PCOS and gluten-related disorders.”

    FACT: A 2002 study from the International Journal of Gynecology & Obstetrics concluded that PCOS did not seem to be associated with celiac disease (6). Overall, more current conclusive evidence is lacking and represents an area for future exploration. 

    MYTH: “A gluten-free diet will result in weight-loss.”

    FACT: There is currently no data indicating that a gluten-free diet can result in planned weight or body composition change.

    MYTH: “Gluten causes harmful inflammation in PCOS.”

    FACT: In general, eating gluten could cause an acute inflammatory response in the body for some people (7,8). Acute inflammation is a beneficial function of a healthy body (9). It’s an immune reaction to help protect the body and can be caused by infection, but also non-infectious factors like consuming glucose, alcohol, toxins, or fatty acids (9,10). It’s likely that eating a wide variety of nutritious foods could balance out the effects of occasional “inflammatory” foods (11). 

    Studies are inconclusive about whether removing gluten from the diet is beneficial for reducing inflammation for someone without a gluten-related disorder (7,13,14). We also don’t know if people with PCOS are more negatively affected by gluten than others. 


    A Gluten-Free Diet May Cause More Harm Than Good for People With PCOS

    It’s important to note that some gluten-free food products lack important nutrients, including fiber (15). Conversely, many gluten-containing products (e.g. whole-grain bread or cereal) tend to be good sources of fiber. Studies have shown that fiber can potentially reduce inflammation (16), improve insulin resistance (17), and reduce the likelihood of developing type 2 diabetes (18,19,20) and cardiovascular disease (21).

    Although more research is needed on the relationship between fiber and PCOS, there is some research showing the benefits of high-fiber diets for PCOS. For example, a review article on the effect of the Mediterranean diet (which includes plenty of fiber rich foods) showed an improvement in inflammation in PCOS (22). Another article (a randomized controlled trial) evaluated the DASH diet for PCOS and found a reduction in insulin resistance (23). It should be mentioned that, along with fiber, there could be other beneficial nutrients from these diets that might explain the positive outcomes.

    Unfortunately, people with PCOS may not be getting enough fiber. Two meta-analyses compared over 12 studies each and found that people with PCOS may eat less fiber than those without the condition (24,25). One of these articles suggested that not eating enough fiber could be a factor in the development of PCOS (24). 

    Research suggests that only those with celiac disease should be following a life-long gluten-free diet (26,27). This is because gluten causes serious damage to the gut of those with celiac disease. 


    When to Recommend a Gluten-Free Diet

    Even though there is no clear reason to avoid gluten with PCOS, it’s still possible that clients may find symptom relief with a gluten-free diet. For example, if they have non-celiac gluten sensitivity or irritable bowel syndrome that is sensitive to certain high FODMAP foods. However, it’s important to investigate whether the client has celiac disease first through proper diagnostic measures before beginning a gluten-free diet. The diagnostic tests can show a false negative if the individual has already started eating gluten-free (28). 

    Even though studies on gluten and PCOS are limited, digestive issues can be common in individuals with PCOS. For this reason, practitioners should assess clients with PCOS for gluten-related disorders including celiac disease, non-gluten sensitivity, and wheat allergy. 

    You can learn more about celiac disease and its symptoms in DSC’s Celiac Disease video course and toolkit. Also, check out the printable client handouts on gluten-free eating to feel more confident in supporting a gluten-free diet if indicated for your patient or client. 


    Key Takeaways 

        • More research is needed on the topic of PCOS and gluten.

        • One study suggested there is no connection between PCOS and celiac disease.

        • The inflammatory effects of gluten can likely be balanced out by eating a variety of foods including those with anti-inflammatory qualities. It’s unknown if people with PCOS have a different reaction to gluten than the general population.

        • People with PCOS (and those following a gluten-free diet) might not be eating enough fiber. Yet, some studies have shown that fiber can help reduce inflammation, improve insulin resistance, and reduce the likelihood of developing type 2 diabetes, and cardiovascular disease, which are all aspects of PCOS.

        • Clients with PCOS should be assessed for celiac disease before beginning a gluten-free diet.

        • Learn about nutrition therapy interventions with more evidence to support those with PCOS in DSC’s PCOS Nutrition Course
      Disclaimer: the information provided in all written materials is for educational purposes only and is not to be used as medical advice or to diagnose or treat a medical disease. It is strictly for informational purposes and is general in nature. Dietitian Success Center Inc. is not responsible and cannot be held liable for any actions or inactions taken related to the information provided. Consult with your local medical provider before implementing any dietary changes. It is hereby understood that the information provided does not replace medical advice provided by your healthcare provider.


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        Dietitian Success Center is THE professional development resource for dietitians and dietetic students. Our mission is to make it easier for dietitians and dietetic students to build expertise. We do this through evidence-based online nutrition courses, community and ready-to-use client handouts. Plus – we give you the tools to start and grow your dietitian private practice! 



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